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Investigation of Mutated in Colorectal Cancer (MCC) Gene Family Evolution History Indicates a Putative Role in Th17/Treg Differentiation
The MCC family of genes plays a role in colorectal cancer development through various immunological pathways, including the Th17/Treg axis. We have previously shown that MCC1 but not MCC2 plays a role in Treg differentiation. Our understanding of the genetic divergence patterns and evolutionary hist...
Autores principales: | Kubick, Norwin, Paszkiewicz, Justyna, Bieńkowska, Irmina, Ławiński, Michał, Horbańczuk, Jarosław Olav, Sacharczuk, Mariusz, Mickael, Michel Edwar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418881/ https://www.ncbi.nlm.nih.gov/pubmed/37569317 http://dx.doi.org/10.3390/ijms241511940 |
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