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Phosphorylation of AMPKα at Ser485/491 Is Dependent on Muscle Contraction and Not Muscle-Specific IGF-I Overexpression

Glucose is an important fuel for highly active skeletal muscles. Increased adenosine monophosphate (AMP)/adenosine triphosphate (ATP) ratios during repetitive contractions trigger AMP-activated protein kinase (AMPK), indicated by phosphorylation of AMPKα(Thr172), which promotes glucose uptake to sup...

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Detalles Bibliográficos
Autores principales: Chou, Chih-Hsuan, Barton, Elisabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418898/
https://www.ncbi.nlm.nih.gov/pubmed/37569325
http://dx.doi.org/10.3390/ijms241511950