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LRG1 Promotes ECM Integrity by Activating the TGF-β Signaling Pathway in Fibroblasts

Leucine-rich alpha-2-glycoprotein 1 (LRG1) mediates skin repair and fibrosis by stimulating the transforming growth factor-beta (TGF-β) signaling pathway. In the present study, we investigated the effect of LRG1 on extracellular matrix (ECM) integrity in fibroblasts, as well as on skin aging. The tr...

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Detalles Bibliográficos
Autores principales: Park, Han Na, Song, Min Ji, Choi, Young Eun, Lee, Dong Hun, Chung, Jin Ho, Lee, Seung-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418909/
https://www.ncbi.nlm.nih.gov/pubmed/37569820
http://dx.doi.org/10.3390/ijms241512445