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Antibody-Drug Conjugates for Breast Cancer Treatment: Emerging Agents, Targets and Future Directions

To achieve the scheme of “magic bullets” in antitumor therapy, antibody-drug conjugates (ADCs) were developed. ADCs consist of antibodies targeting tumor-specific antigens, chemical linkers, and cytotoxic payloads that powerfully kill cancer cells. With the approval of ado-trastuzumab emtansine (T-D...

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Detalles Bibliográficos
Autores principales: Yang, Tinglin, Li, Wenhui, Huang, Tao, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418918/
https://www.ncbi.nlm.nih.gov/pubmed/37569276
http://dx.doi.org/10.3390/ijms241511903