Cargando…

Core Fucosylation Mediated by the FucT-8 Enzyme Affects TRAIL-Induced Apoptosis and Sensitivity to Chemotherapy in Human SW480 and SW620 Colorectal Cancer Cells

Epithelial cells can undergo apoptosis by manipulating the balance between pro-survival and apoptotic signals. In this work, we show that TRAIL-induced apoptosis can be differentially regulated by the expression of α(1,6)fucosyltransferase (FucT-8), the only enzyme in mammals that transfers the α(1,...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Cortés, Rubén, Correa Pardo, Isabel, Muinelo-Romay, Laura, Fernández-Briera, Almudena, Gil-Martín, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418920/
https://www.ncbi.nlm.nih.gov/pubmed/37569254
http://dx.doi.org/10.3390/ijms241511879