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Treprostinil Reconstitutes Mitochondrial Organisation and Structure in Idiopathic Pulmonary Fibrosis Cells

Idiopathic pulmonary fibrosis (IPF) presents as an incurable change in the lung tissue and mitochondrial dysfunction of unknown origin. Treprostinil, a prostacyclin analogue, has been suggested for IPF therapy. This study assessed the effect of treprostinil on the cAMP signalling and mitochondrial a...

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Detalles Bibliográficos
Autores principales: Fang, Lei, Chen, Wei-Chih, Jaksch, Peter, Molino, Antonio, Saglia, Alessandro, Roth, Michael, Lambers, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418929/
https://www.ncbi.nlm.nih.gov/pubmed/37569523
http://dx.doi.org/10.3390/ijms241512148