Knockdown of PTK7 Reduces the Oncogenic Potential of Breast Cancer Cells by Impeding Receptor Tyrosine Kinase Signaling

Protein tyrosine kinase 7 (PTK7), a catalytically defective receptor tyrosine kinase (RTK), is often upregulated in various cancers. This study aimed to validate PTK7 as a target for breast cancer (BC) and investigate its oncogenic signaling mechanism. BC tissue analysis showed significantly elevate...

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Detalles Bibliográficos
Autores principales: Shin, Won-Sik, Oh, Si Won, Park, Han Na, Kim, Jae Hoon, Lee, Seung-Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418930/
https://www.ncbi.nlm.nih.gov/pubmed/37569547
http://dx.doi.org/10.3390/ijms241512173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418930/
https://www.ncbi.nlm.nih.gov/pubmed/37569547
http://dx.doi.org/10.3390/ijms241512173

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