Histone Deacetylase Inhibitor (SAHA) Reduces Mortality in an Endotoxemia Mouse Model by Suppressing Glycolysis

Sepsis is a life-threatening medical emergency triggered by excessive inflammation in response to an infection. High mortality rates and limited therapeutic options pose significant challenges in sepsis treatment. Histone deacetylase inhibitors (HDACi), such as suberoylanilide hydroxamic acid (SAHA)...

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Detalles Bibliográficos
Autores principales: Wu, Yunchen, He, Yudan, Liu, Chen, Ehle, Charlotte, Iyer-Bierhoff, Aishwarya, Liu, Bing, Heinzel, Thorsten, Xing, Shaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418975/
https://www.ncbi.nlm.nih.gov/pubmed/37569823
http://dx.doi.org/10.3390/ijms241512448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418975/
https://www.ncbi.nlm.nih.gov/pubmed/37569823
http://dx.doi.org/10.3390/ijms241512448

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