Synthesis and Evaluation of (177)Lu-DOTA-PD-L1-i and (225)Ac-HEHA-PD-L1-i as Potential Radiopharmaceuticals for Tumor Microenvironment-Targeted Radiotherapy

Current cancer therapies focus on reducing immunosuppression and remodeling the tumor microenvironment to inhibit metastasis, cancer progression, and therapeutic resistance. Programmed death receptor 1 (PD-1) is expressed on immune T cells and is one of the so-called checkpoint proteins that can sup...

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Detalles Bibliográficos
Autores principales: Luna-Gutiérrez, Myrna, Cruz-Nova, Pedro, Jiménez-Mancilla, Nallely, Oros-Pantoja, Rigoberto, Lara-Almazán, Nancy, Santos-Cuevas, Clara, Azorín-Vega, Erika, Ocampo-García, Blanca, Ferro-Flores, Guillermina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418980/
https://www.ncbi.nlm.nih.gov/pubmed/37569758
http://dx.doi.org/10.3390/ijms241512382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418980/
https://www.ncbi.nlm.nih.gov/pubmed/37569758
http://dx.doi.org/10.3390/ijms241512382

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