Dynamics of the Second Extracellular Loop Control Transducer Coupling of Peptide-Activated GPCRs

Many peptide-activated rhodopsin-like GPCRs share a β-hairpin folding motif in the extracellular loop 2 (ECL2), which interacts with the peptide ligand while at the same time being connected to transmembrane helix 3 (TM3) via a highly conserved disulfide bond. Currently, it remains unknown whether t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wygas, Marcel M., Laugwitz, Jeannette M., Schmidt, Peter, Elgeti, Matthias, Kaiser, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419011/
https://www.ncbi.nlm.nih.gov/pubmed/37569573
http://dx.doi.org/10.3390/ijms241512197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419011/
https://www.ncbi.nlm.nih.gov/pubmed/37569573
http://dx.doi.org/10.3390/ijms241512197

Ejemplares similares