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Dynamics of the Second Extracellular Loop Control Transducer Coupling of Peptide-Activated GPCRs

Many peptide-activated rhodopsin-like GPCRs share a β-hairpin folding motif in the extracellular loop 2 (ECL2), which interacts with the peptide ligand while at the same time being connected to transmembrane helix 3 (TM3) via a highly conserved disulfide bond. Currently, it remains unknown whether t...

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Detalles Bibliográficos
Autores principales:	Wygas, Marcel M., Laugwitz, Jeannette M., Schmidt, Peter, Elgeti, Matthias, Kaiser, Anette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419011/ https://www.ncbi.nlm.nih.gov/pubmed/37569573 http://dx.doi.org/10.3390/ijms241512197

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