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Investigation of the Mitigation of DMSO-Induced Cytotoxicity by Hyaluronic Acid following Cryopreservation of Human Nucleus Pulposus Cells

To develop an off-the-shelf therapeutic product for intervertebral disc (IVD) repair using nucleus pulposus cells (NPCs), it is beneficial to mitigate dimethyl sulfoxide (DMSO)-induced cytotoxicity caused by intracellular reactive oxygen species (ROS). Hyaluronic acid (HA) has been shown to protect...

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Detalles Bibliográficos
Autores principales: Munesada, Daiki, Sakai, Daisuke, Nakamura, Yoshihiko, Schol, Jordy, Matsushita, Erika, Tamagawa, Shota, Sako, Kosuke, Ogasawara, Shota, Sato, Masato, Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419032/
https://www.ncbi.nlm.nih.gov/pubmed/37569664
http://dx.doi.org/10.3390/ijms241512289