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Indoxyl Sulfate Administration during Pregnancy Contributes to Renal Injury and Increased Blood–Brain Barrier Permeability

Rates of pregnancy-related acute kidney injury (PR-AKI) have increased in the U.S over the past two decades, but how PR-AKI affects the blood–brain barrier (BBB) is understudied. AKI is associated with increased amounts of uremic toxins, like indoxyl sulfate (I.S), whose chronic administration leads...

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Detalles Bibliográficos
Autores principales: Griffin, Ashley, Berry, Brittany, Spencer, Shauna-Kay, Bowles, Teylor, Wallace, Kedra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419049/
https://www.ncbi.nlm.nih.gov/pubmed/37569342
http://dx.doi.org/10.3390/ijms241511968