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Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C

Cardiac muscle contraction is regulated via Ca(2+) exchange with the hetero-trimeric troponin complex located on the thin filament. Binding of Ca(2+) to cardiac troponin C, a Ca(2+) sensing subunit within the troponin complex, results in a series of conformational re-arrangements among the thin fila...

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Detalles Bibliográficos
Autores principales: Tikunova, Svetlana B., Thuma, Jenna, Davis, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419064/
https://www.ncbi.nlm.nih.gov/pubmed/37569724
http://dx.doi.org/10.3390/ijms241512349