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Mouse Models of Cardiomyopathies Caused by Mutations in Troponin C
Cardiac muscle contraction is regulated via Ca(2+) exchange with the hetero-trimeric troponin complex located on the thin filament. Binding of Ca(2+) to cardiac troponin C, a Ca(2+) sensing subunit within the troponin complex, results in a series of conformational re-arrangements among the thin fila...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419064/ https://www.ncbi.nlm.nih.gov/pubmed/37569724 http://dx.doi.org/10.3390/ijms241512349 |