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Biophysical Profiling of Sickle Cell Disease Using Holographic Cytometry and Deep Learning

Sickle cell disease (SCD) is an inherited hematological disorder associated with high mortality rates, particularly in sub-Saharan Africa. SCD arises due to the polymerization of sickle hemoglobin, which reduces flexibility of red blood cells (RBCs), causing blood vessel occlusion and leading to sev...

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Detalles Bibliográficos
Autores principales: Chen, Cindy X., Funkenbusch, George T., Wax, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419148/
https://www.ncbi.nlm.nih.gov/pubmed/37569260
http://dx.doi.org/10.3390/ijms241511885