Cargando…

Dysregulated miRNA and mRNA Expression Affect Overlapping Pathways in a Huntington’s Disease Model

Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in the Huntingtin gene. Transcriptional dysregulation is one of the main cellular processes affected by mutant Huntingtin (mHtt). In this study, we investigate the alterations in miR...

Descripción completa

Detalles Bibliográficos
Autores principales: Zsindely, Nóra, Nagy, Gábor, Siági, Fruzsina, Farkas, Anita, Bodai, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419151/
https://www.ncbi.nlm.nih.gov/pubmed/37569316
http://dx.doi.org/10.3390/ijms241511942