Radotinib Decreases Prion Propagation and Prolongs Survival Times in Models of Prion Disease

The conversion of cellular prion protein (PrP(C)) into pathogenic prion isoforms (PrP(Sc)) and the mutation of PRNP are definite causes of prion diseases. Unfortunately, without exception, prion diseases are untreatable and fatal neurodegenerative disorders; therefore, one area of research focuses o...

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Detalles Bibliográficos
Autores principales: Choi, Yeong-Gon, Jang, Byungki, Park, Jeong-Ho, Choi, Min-Woo, Lee, Gong Yeal, Cho, Dae Jin, Kim, Hong Youp, Lim, Hae Kyoung, Lee, Won Jae, Choi, Eun-Kyoung, Kim, Yong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419185/
https://www.ncbi.nlm.nih.gov/pubmed/37569615
http://dx.doi.org/10.3390/ijms241512241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419185/
https://www.ncbi.nlm.nih.gov/pubmed/37569615
http://dx.doi.org/10.3390/ijms241512241

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