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Linked-read based analysis of the medulloblastoma genome

INTRODUCTION: Medulloblastoma is the most common type of malignant pediatric brain tumor with group 4 medulloblastomas (G4 MBs) accounting for 40% of cases. However, the molecular mechanisms that underlie this subgroup are still poorly understood. Point mutations are detected in a large number of ge...

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Detalles Bibliográficos
Autores principales: Zwaig, Melissa, Johnston, Michael J., Lee, John J.Y., Farooq, Hamza, Gallo, Marco, Jabado, Nada, Taylor, Michael D., Ragoussis, Jiannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419201/
https://www.ncbi.nlm.nih.gov/pubmed/37576901
http://dx.doi.org/10.3389/fonc.2023.1221611