Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes

Topoisomerases, common targets for anti-cancer therapeutics, are crucial enzymes for DNA replication, transcription, and many other aspects of DNA metabolism. The potential anti-cancer effects of thiosemicarbazones (TSC) and metal–TSC complexes have been demonstrated to target several biological pro...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaohua, Fielding, Lauren A., Davis, Hunter, Carroll, William, Lisic, Edward C., Deweese, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419228/
https://www.ncbi.nlm.nih.gov/pubmed/37569386
http://dx.doi.org/10.3390/ijms241512010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419228/
https://www.ncbi.nlm.nih.gov/pubmed/37569386
http://dx.doi.org/10.3390/ijms241512010

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