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Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes
Topoisomerases, common targets for anti-cancer therapeutics, are crucial enzymes for DNA replication, transcription, and many other aspects of DNA metabolism. The potential anti-cancer effects of thiosemicarbazones (TSC) and metal–TSC complexes have been demonstrated to target several biological pro...
Autores principales: | Jiang, Xiaohua, Fielding, Lauren A., Davis, Hunter, Carroll, William, Lisic, Edward C., Deweese, Joseph E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419228/ https://www.ncbi.nlm.nih.gov/pubmed/37569386 http://dx.doi.org/10.3390/ijms241512010 |
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