Evidence for Hypoxia-Induced Shift in ATP Production from Glycolysis to Mitochondrial Respiration in Pulmonary Artery Smooth Muscle Cells in Pulmonary Arterial Hypertension

Background: The metabolic state of pulmonary artery smooth muscle cells (PASMCs) from patients with pulmonary arterial hypertension (PAH) is not well understood. In this study, we examined the balance between glycolysis and mitochondrial respiration in non-PAH-PASMCs and PAH-PASMCs under normoxia an...

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Detalles Bibliográficos
Autores principales: Akagi, Satoshi, Nakamura, Kazufumi, Kondo, Megumi, Hirohata, Satoshi, Udono, Heiichiro, Nishida, Mikako, Saito, Yukihiro, Yoshida, Masashi, Miyoshi, Toru, Ito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419513/
https://www.ncbi.nlm.nih.gov/pubmed/37568430
http://dx.doi.org/10.3390/jcm12155028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419513/
https://www.ncbi.nlm.nih.gov/pubmed/37568430
http://dx.doi.org/10.3390/jcm12155028

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