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Evidence for Hypoxia-Induced Shift in ATP Production from Glycolysis to Mitochondrial Respiration in Pulmonary Artery Smooth Muscle Cells in Pulmonary Arterial Hypertension
Background: The metabolic state of pulmonary artery smooth muscle cells (PASMCs) from patients with pulmonary arterial hypertension (PAH) is not well understood. In this study, we examined the balance between glycolysis and mitochondrial respiration in non-PAH-PASMCs and PAH-PASMCs under normoxia an...
Autores principales: | Akagi, Satoshi, Nakamura, Kazufumi, Kondo, Megumi, Hirohata, Satoshi, Udono, Heiichiro, Nishida, Mikako, Saito, Yukihiro, Yoshida, Masashi, Miyoshi, Toru, Ito, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419513/ https://www.ncbi.nlm.nih.gov/pubmed/37568430 http://dx.doi.org/10.3390/jcm12155028 |
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