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Augmentation of Cathepsin Isoforms in Diabetic db/db Mouse Kidneys Is Associated with an Increase in Renal MARCKS Expression and Proteolysis

The expression of the myristoylated alanine-rich C-kinase substrate (MARCKS) family of proteins in the kidneys plays an important role in the regulation of the renal epithelial sodium channel (ENaC) and hence overall blood pressure regulation. The function of MARCKS is regulated by post-translationa...

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Detalles Bibliográficos
Autores principales: Gholam, Mohammed F., Bala, Niharika, Dogan, Yunus E., Alli, Abdel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419664/
https://www.ncbi.nlm.nih.gov/pubmed/37569859
http://dx.doi.org/10.3390/ijms241512484