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Impact of Somatic DNA Repair Mutations on the Clinical Outcomes of Bone Metastases from Castration-Resistant Prostate Cancer

Up to 80% of castration-resistant prostate cancer (CRPC) patients develop bone metastases during the natural history of disease and about 25% harbor mutations in DNA damage repair (DDR) genes. This retrospective observational study evaluated the prevalence of DDR alterations in CRPC patients and the...

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Detalles Bibliográficos
Autores principales: Cursano, Maria Concetta, Giunta, Emilio Francesco, Scarpi, Emanuela, Casadei, Chiara, Virga, Alessandra, Ulivi, Paola, Bleve, Sara, Brighi, Nicole, Ravaglia, Giorgia, Pantano, Francesco, Conteduca, Vincenza, Santini, Daniele, De Giorgi, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419855/
https://www.ncbi.nlm.nih.gov/pubmed/37569810
http://dx.doi.org/10.3390/ijms241512436