Sirtuin1-Mediated Deacetylation of Hypothalamic TTF-1 Contributes to the Energy Deficiency Response

TTF-1 stimulates appetite by regulating the expression of agouti-related peptide (AgRP) and proopiomelanocortin (POMC) genes in the hypothalamus of starving animals. However, the mechanism underlying TTF-1’s response to decreased energy levels remains elusive. Here, we provide evidence that the NAD(...

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Detalles Bibliográficos
Autores principales: Kang, Dasol, Yang, Hye Rim, Kim, Dong Hee, Kim, Kwang Kon, Jeong, Bora, Park, Byong Seo, Park, Jeong Woo, Kim, Jae Geun, Lee, Byung Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419861/
https://www.ncbi.nlm.nih.gov/pubmed/37569904
http://dx.doi.org/10.3390/ijms241512530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419861/
https://www.ncbi.nlm.nih.gov/pubmed/37569904
http://dx.doi.org/10.3390/ijms241512530

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