A Novel Betulinic Acid Analogue: Synthesis, Solubility, Antitumor Activity and Pharmacokinetic Study in Rats

Betulinic acid (BA) and betulin (BE) are naturally pentacyclic triterpenes with documented biological activities, especially antitumor and anti-inflammatory activity. However, their bioavailability in vivo is not satisfactory in terms of medical applications. Thus, to improve the solubility and bioa...

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Detalles Bibliográficos
Autores principales: Liang, Yucen, Zhu, Meixuan, Xu, Tao, Ding, Weimin, Chen, Min, Wang, Yang, Zheng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419975/
https://www.ncbi.nlm.nih.gov/pubmed/37570685
http://dx.doi.org/10.3390/molecules28155715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419975/
https://www.ncbi.nlm.nih.gov/pubmed/37570685
http://dx.doi.org/10.3390/molecules28155715

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