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A Novel Betulinic Acid Analogue: Synthesis, Solubility, Antitumor Activity and Pharmacokinetic Study in Rats

Betulinic acid (BA) and betulin (BE) are naturally pentacyclic triterpenes with documented biological activities, especially antitumor and anti-inflammatory activity. However, their bioavailability in vivo is not satisfactory in terms of medical applications. Thus, to improve the solubility and bioa...

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Detalles Bibliográficos
Autores principales:	Liang, Yucen, Zhu, Meixuan, Xu, Tao, Ding, Weimin, Chen, Min, Wang, Yang, Zheng, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10419975/ https://www.ncbi.nlm.nih.gov/pubmed/37570685 http://dx.doi.org/10.3390/molecules28155715

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