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Development of tolerance to chemokine receptor antagonists: current paradigms and the need for further investigation
Chemokine G-protein coupled receptors are validated drug targets for many diseases, including cancer, neurological, and inflammatory disorders. Despite much time and effort spent on therapeutic development, very few chemokine receptor antagonists are approved for clinical use. Among potential reason...
Autores principales: | Grudzien, Patrick, Neufeld, Henry, Ebe Eyenga, Mbasogo, Gaponenko, Vadim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420067/ https://www.ncbi.nlm.nih.gov/pubmed/37575219 http://dx.doi.org/10.3389/fimmu.2023.1184014 |
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