Pyronaridine as a Bromodomain-Containing Protein 4-N-Terminal Bromodomain (BRD4-BD1) Inhibitor: In Silico Database Mining, Molecular Docking, and Molecular Dynamics Simulation

BRD4 (bromodomain-containing protein 4) is an epigenetic reader that realizes histone proteins and promotes the transcription of genes linked to cancer progression and non-cancer diseases such as acute heart failure and severe inflammation. The highly conserved N-terminal bromodomain (BD1) recognize...

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Detalles Bibliográficos
Autores principales: Ibrahim, Mahmoud A. A., Abdelhamid, Mahmoud M. H., Abdeljawaad, Khlood A. A., Abdelrahman, Alaa H. M., Mekhemer, Gamal A. H., Sidhom, Peter A., Sayed, Shaban R. M., Paré, Paul W., Hegazy, Mohamed-Elamir F., Shoeib, Tamer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420099/
https://www.ncbi.nlm.nih.gov/pubmed/37570684
http://dx.doi.org/10.3390/molecules28155713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420099/
https://www.ncbi.nlm.nih.gov/pubmed/37570684
http://dx.doi.org/10.3390/molecules28155713

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