An Oxidant-Free and Mild Strategy for Quinazolin-4(3H)-One Synthesis via CuAAC/Ring Cleavage Reaction

An oxidant-free and highly efficient synthesis of phenolic quinazolin-4(3H)-ones was achieved by simply stirring a mixture of 2-aminobenzamides, sulfonyl azides, and terminal alkynes. The intermediate N-sulfonylketenimine underwent two nucleophilic additions and the sulfonyl group eliminated through...

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Detalles Bibliográficos
Autores principales: He, Yueling, Yang, Zhongtao, Luo, Danyang, Luo, Xiai, Chen, Xiaodong, Yang, Weiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420183/
https://www.ncbi.nlm.nih.gov/pubmed/37570705
http://dx.doi.org/10.3390/molecules28155734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420183/
https://www.ncbi.nlm.nih.gov/pubmed/37570705
http://dx.doi.org/10.3390/molecules28155734

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