Unlocking the Potential: Novel NSAIDs Hybrids Unleash Chemopreventive Power toward Liver Cancer Cells through Nrf2, NF-κB, and MAPK Signaling Pathways

HCC is a highly aggressive malignancy with limited treatment options. In this study, novel conjugates of non-steroidal anti-inflammatory drugs (NSAIDs)—Ibuprofen and Ketoprofen—with oleanolic acid oximes derivatives (OAO) were synthesized, and their activity as modulators of signaling pathways invol...

Descripción completa

Detalles Bibliográficos
Autores principales: Narożna, Maria, Krajka-Kuźniak, Violetta, Bednarczyk-Cwynar, Barbara, Baer-Dubowska, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420225/
https://www.ncbi.nlm.nih.gov/pubmed/37570726
http://dx.doi.org/10.3390/molecules28155759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420225/
https://www.ncbi.nlm.nih.gov/pubmed/37570726
http://dx.doi.org/10.3390/molecules28155759

Ejemplares similares