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Unlocking the Potential: Novel NSAIDs Hybrids Unleash Chemopreventive Power toward Liver Cancer Cells through Nrf2, NF-κB, and MAPK Signaling Pathways

HCC is a highly aggressive malignancy with limited treatment options. In this study, novel conjugates of non-steroidal anti-inflammatory drugs (NSAIDs)—Ibuprofen and Ketoprofen—with oleanolic acid oximes derivatives (OAO) were synthesized, and their activity as modulators of signaling pathways invol...

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Detalles Bibliográficos
Autores principales:	Narożna, Maria, Krajka-Kuźniak, Violetta, Bednarczyk-Cwynar, Barbara, Baer-Dubowska, Wanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420225/ https://www.ncbi.nlm.nih.gov/pubmed/37570726 http://dx.doi.org/10.3390/molecules28155759

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