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Generating Potential Protein-Protein Interaction Inhibitor Molecules Based on Physicochemical Properties

Protein-protein interactions (PPIs) are associated with various diseases; hence, they are important targets in drug discovery. However, the physicochemical empirical properties of PPI-targeted drugs are distinct from those of conventional small molecule oral pharmaceuticals, which adhere to the ”rul...

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Detalles Bibliográficos
Autores principales: Ohue, Masahito, Kojima, Yuki, Kosugi, Takatsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420264/
https://www.ncbi.nlm.nih.gov/pubmed/37570623
http://dx.doi.org/10.3390/molecules28155652