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Generating Potential Protein-Protein Interaction Inhibitor Molecules Based on Physicochemical Properties
Protein-protein interactions (PPIs) are associated with various diseases; hence, they are important targets in drug discovery. However, the physicochemical empirical properties of PPI-targeted drugs are distinct from those of conventional small molecule oral pharmaceuticals, which adhere to the ”rul...
Autores principales: | Ohue, Masahito, Kojima, Yuki, Kosugi, Takatsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420264/ https://www.ncbi.nlm.nih.gov/pubmed/37570623 http://dx.doi.org/10.3390/molecules28155652 |
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