Friedel–Crafts Reaction of Acylsilanes: Highly Chemoselective Synthesis of 1-Hydroxy-bis(indolyl)methanes and 1-Silyl-bis(indolyl)methanes Derivatives

A novel double Friedel–Crafts reaction of acylsilanes in water is described. This strategy enables synthesis of bis(indolyl)methane derivatives with 1-hydroxy or 1-silyl substituents in moderate to high yield. Compared to the 1-silyl-bis(indolyl)methane derivatives from indole substrate, 1-hydroxy-b...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qi, Liang, Xiu-Xia, Zhang, Wang, Han, Man-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420641/
https://www.ncbi.nlm.nih.gov/pubmed/37570655
http://dx.doi.org/10.3390/molecules28155685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420641/
https://www.ncbi.nlm.nih.gov/pubmed/37570655
http://dx.doi.org/10.3390/molecules28155685

Ejemplares similares