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Synthesis and Biological Evaluation of New Quinoline and Anthranilic Acid Derivatives as Potential Quorum Sensing Inhibitors

Inhibiting quorum sensing (QS), a central communication system, is a promising strategy to combat bacterial pathogens without antibiotics. Here, we designed novel hybrid compounds targeting the PQS (Pseudomonas quinolone signal)-dependent quorum sensing (QS) of Pseudomonas aeruginosa that is one of...

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Detalles Bibliográficos
Autores principales: Perković, Ivana, Poljak, Tanja, Savijoki, Kirsi, Varmanen, Pekka, Maravić-Vlahoviček, Gordana, Beus, Maja, Kučević, Anja, Džajić, Ivan, Rajić, Zrinka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420644/
https://www.ncbi.nlm.nih.gov/pubmed/37570836
http://dx.doi.org/10.3390/molecules28155866