Domino Aldol-S(N)Ar-Dehydration Sequence for [3+3] Annulations to Prepare Quinolin-2(1H)-ones and 1,8-Naphthyridin-2(1H)-ones

A domino aldol-S(N)Ar-dehydration [3+3] annulation strategy has been utilized to fuse six-membered cyclic amides onto aromatic substrates. 2-Arylacetamides have been reacted with 2-fluorobenzaldehyde derivatives activated toward S(N)Ar reaction by an electron-withdrawing substituent (NO(2), CN, CF(3...

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Detalles Bibliográficos
Autores principales: Fobi, Kwabena, Ametsetor, Ebenezer, Bunce, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420682/
https://www.ncbi.nlm.nih.gov/pubmed/37570826
http://dx.doi.org/10.3390/molecules28155856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420682/
https://www.ncbi.nlm.nih.gov/pubmed/37570826
http://dx.doi.org/10.3390/molecules28155856

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