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Mechanistic Action of Cell Cycle Arrest and Intrinsic Apoptosis via Inhibiting Akt/mTOR and Activation of p38-MAPK Signaling Pathways in Hep3B Liver Cancer Cells by Prunetrin—A Flavonoid with Therapeutic Potential

Hepatocellular carcinoma (HCC) has a poor prognosis and a low survival rate. Drugs without side effects are desperately needed since chemotherapy has a negative effect on the host cells. Previous research has firmly established that plant-based compounds have significant bioactivities without a nega...

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Detalles Bibliográficos
Autores principales: Abusaliya, Abuyaseer, Jeong, Se Hyo, Bhosale, Pritam Bhagwan, Kim, Hun Hwan, Park, Min Yeong, Kim, Eunhye, Won, Chung Kil, Park, Kwang Il, Heo, Jeong Doo, Kim, Hyun Wook, Ahn, Meejung, Seong, Je Kyung, Kim, Gon Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10420889/
https://www.ncbi.nlm.nih.gov/pubmed/37571343
http://dx.doi.org/10.3390/nu15153407