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DDM1-mediated R-loop resolution and H2A.Z exclusion facilitates heterochromatin formation in Arabidopsis

Programmed constitutive heterochromatin silencing is essential for eukaryotic genome regulation, yet the initial step of this process is ambiguous. A large proportion of R-loops (RNA:DNA hybrids) had been unexpectedly identified within Arabidopsis pericentromeric heterochromatin with unknown functio...

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Detalles Bibliográficos
Autores principales: Zhou, Jincong, Lei, Xue, Shafiq, Sarfraz, Zhang, Weifeng, Li, Qin, Li, Kuan, Zhu, Jiafu, Dong, Zhicheng, He, Xin-jian, Sun, Qianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421056/
https://www.ncbi.nlm.nih.gov/pubmed/37566662
http://dx.doi.org/10.1126/sciadv.adg2699