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[(125)I]INFT: Synthesis and Evaluation of a New Imaging Agent for Tau Protein in Post-Mortem Human Alzheimer’s Disease Brain

Aggregation of Tau protein into paired helical filaments causing neurofibrillary tangles (NFT) is a neuropathological feature in Alzheimer’s disease (AD). This study aimed to develop and evaluate the effectiveness of a novel radioiodinated tracer, 4-[(125)I]iodo-3-(1H-pyrrolo[2,3-c]pyridine-1-yl)pyr...

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Detalles Bibliográficos
Autores principales: Limpengco, Roz R., Liang, Christopher, Sandhu, Yasmin K., Mukherjee, Jogeshwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421386/
https://www.ncbi.nlm.nih.gov/pubmed/37570739
http://dx.doi.org/10.3390/molecules28155769