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Pentafuhalol-B, a Phlorotannin from Brown Algae, Strongly Inhibits the PLK-1 Overexpression in Cancer Cells as Revealed by Computational Analysis

Polo-like kinase-1 (PLK-1) is an essential mitotic serine/threonine (Ser/Thr) kinase that belongs to the Polo-like kinase (PLK) family and is overexpressed in non-small cell lung cancer (NSCLC) via promotion of cell division. Therefore, PLK-1 may act as a promising target for the therapeutic cure of...

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Detalles Bibliográficos
Autores principales: Ansari, Waseem Ahmad, Rab, Safia Obaidur, Saquib, Mohammad, Sarfraz, Aqib, Hussain, Mohd Kamil, Akhtar, Mohd Sayeed, Ahmad, Irfan, Khan, Mohammad Faheem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421442/
https://www.ncbi.nlm.nih.gov/pubmed/37570823
http://dx.doi.org/10.3390/molecules28155853