Solid-phase capture and profiling of open chromatin by spatial ATAC

Current methods for epigenomic profiling are limited in their ability to obtain genome-wide information with spatial resolution. We introduce spatial ATAC, a method that integrates transposase-accessible chromatin profiling in tissue sections with barcoded solid-phase capture to perform spatially re...

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Detalles Bibliográficos
Autores principales: Llorens-Bobadilla, Enric, Zamboni, Margherita, Marklund, Maja, Bhalla, Nayanika, Chen, Xinsong, Hartman, Johan, Frisén, Jonas, Ståhl, Patrik L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421738/
https://www.ncbi.nlm.nih.gov/pubmed/36604544
http://dx.doi.org/10.1038/s41587-022-01603-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421738/
https://www.ncbi.nlm.nih.gov/pubmed/36604544
http://dx.doi.org/10.1038/s41587-022-01603-9

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