Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms

Engineered live bacteria could provide a new modality for treating lung infections, a major cause of mortality worldwide. In the present study, we engineered a genome-reduced human lung bacterium, Mycoplasma pneumoniae, to treat ventilator-associated pneumonia, a disease with high hospital mortality...

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Detalles Bibliográficos
Autores principales: Mazzolini, Rocco, Rodríguez-Arce, Irene, Fernández-Barat, Laia, Piñero-Lambea, Carlos, Garrido, Victoria, Rebollada-Merino, Agustín, Motos, Anna, Torres, Antoni, Grilló, Maria Jesús, Serrano, Luis, Lluch-Senar, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421741/
https://www.ncbi.nlm.nih.gov/pubmed/36658340
http://dx.doi.org/10.1038/s41587-022-01584-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421741/
https://www.ncbi.nlm.nih.gov/pubmed/36658340
http://dx.doi.org/10.1038/s41587-022-01584-9

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