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FOXO 1 deletion in chondrocytes rescues diabetes-impaired fracture healing by restoring angiogenesis and reducing apoptosis

INTRODUCTION: Diabetes mellitus is associated with higher risks of long bone and jaw fractures. It is also associated with a higher incidence of delayed union or non-union. Our previous investigations concluded that a dominant mechanism was the premature loss of cartilage during endochondral bone fo...

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Detalles Bibliográficos
Autores principales: Alharbi, Mohammed A., Graves, Dana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421747/
https://www.ncbi.nlm.nih.gov/pubmed/37576976
http://dx.doi.org/10.3389/fendo.2023.1136117