Fibroblast activation in response to TGFβ1 is modulated by co-culture with endothelial cells in a vascular organ-on-chip platform

Background: Tissue fibrosis is a major healthcare burden that affects various organs in the body for which no effective treatments exist. An underlying, emerging theme across organs and tissue types at early stages of fibrosis is the activation of pericytes and/or fibroblasts in the perivascular spa...

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Detalles Bibliográficos
Autores principales: Luu, Rebeccah J., Hoefler, B. Christopher, Gard, Ashley L., Ritenour, Casey R., Rogers, Miles T., Kim, Ernest S., Coppeta, Jonathan R., Cain, Brian P., Isenberg, Brett C., Azizgolshani, Hesham, Fajardo-Ramirez, Oscar R., García-Cardeña, Guillermo, Lech, Matthew P., Tomlinson, Lindsay, Charest, Joseph L., Williams, Corin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421749/
https://www.ncbi.nlm.nih.gov/pubmed/37577751
http://dx.doi.org/10.3389/fmolb.2023.1160851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421749/
https://www.ncbi.nlm.nih.gov/pubmed/37577751
http://dx.doi.org/10.3389/fmolb.2023.1160851

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