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Blood taken immediately after fatal resuscitation attempts yields higher quality DNA for genetic studies as compared to autopsy samples

BACKGROUND: The out-of-hospital cardiac arrest (OHCA) in the young may be associated with a genetic predisposition which is relevant even for genetic counseling of relatives. The identification of genetic variants depends on the availability of intact genomic DNA. DNA from autopsy may be not availab...

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Detalles Bibliográficos
Autores principales: Stanasiuk, Caroline, Milting, Hendrik, Homm, Sören, Persson, Jan, Holtz, Lars, Wittmer, Axel, Fox, Henrik, Laser, Thorsten, Knöll, Ralph, Pohl, Greta Marie, Paluszkiewicz, Lech, Jakob, Thomas, Bachmann-Mennenga, Bernd, Henzler, Dietrich, Grautoff, Steffen, Veit, Gunter, Klingel, Karin, Hori, Erika, Kellner, Udo, Karger, Bernd, Schlepper, Stefanie, Pfeiffer, Heidi, Gummert, Jan, Gärtner, Anna, Tiesmeier, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421769/
https://www.ncbi.nlm.nih.gov/pubmed/36773088
http://dx.doi.org/10.1007/s00414-023-02966-7