Presymptomatic grey matter alterations in ALS kindreds: a computational neuroimaging study of asymptomatic C9orf72 and SOD1 mutation carriers

BACKGROUND: The characterisation of presymptomatic disease-burden patterns in asymptomatic mutation carriers has a dual academic and clinical relevance. The understanding of disease propagation mechanisms is of considerable conceptual interests, and defining the optimal time of pharmacological inter...

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Detalles Bibliográficos
Autores principales: Bede, Peter, Lulé, Dorothée, Müller, Hans-Peter, Tan, Ee Ling, Dorst, Johannes, Ludolph, Albert C., Kassubek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421803/
https://www.ncbi.nlm.nih.gov/pubmed/37178170
http://dx.doi.org/10.1007/s00415-023-11764-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421803/
https://www.ncbi.nlm.nih.gov/pubmed/37178170
http://dx.doi.org/10.1007/s00415-023-11764-5

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