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TERT mutations-associated alterations in clinical characteristics, immune environment and therapy response in glioblastomas

OBJECTIVE TERT: is the most frequently mutated gene in adult glioblastomas (GBMs) defined by the 2021 World Health Organization classification system. The present study aims to explore differences in clinical characteristics and immune microenvironment between TERT mutant and wild-type GBM. METHODS:...

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Detalles Bibliográficos
Autores principales: Tang, Feng, Chen, Xi, Liu, Jin-Sheng, Liu, Zhen-Yuan, Yang, Jin-Zhou, Wang, Ze-Fen, Li, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421840/
https://www.ncbi.nlm.nih.gov/pubmed/37566174
http://dx.doi.org/10.1007/s12672-023-00760-w