Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy

Individuals with Parkinson’s disease (PD) typically receive a diagnosis once they have developed motor symptoms, at which point there is already significant loss of substantia nigra dopamine neurons, α-synuclein accumulation in surviving neurons, and neuroinflammation. Consequently, the point of cli...

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Detalles Bibliográficos
Autores principales: Van Laar, Amber D., Webb, Katherine R., Keeney, Matthew T., Van Laar, Victor S., Zharikov, Alevtina, Burton, Edward A., Hastings, Teresa G., Glajch, Kelly E., Hirst, Warren D., Greenamyre, J. Timothy, Rocha, Emily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421849/
https://www.ncbi.nlm.nih.gov/pubmed/37567894
http://dx.doi.org/10.1038/s41531-023-00561-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421849/
https://www.ncbi.nlm.nih.gov/pubmed/37567894
http://dx.doi.org/10.1038/s41531-023-00561-6

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